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But with an eye on the wallet. Although it seems that the trend of booking holidays, for Italians, is growing, this is even more true if we take into account nearby destinations. And for limited periods of time. Therefore, the holidays hit and run by a few days increase, while the more substantial ones, from a week upwards, remain stable after all.
With our mini-guide to the most beautiful seaside resorts and especially where to spend little , easily accessible and less traveled by mass tourism you will discover that it is possible to enjoy, at least once a year, a period of detachment a little longer than a handful of days. The Bel Paese would suffice, in itself, to provide all the necessary ideas for a rich and interesting selection of summer destinations kissed by sun and sea.
Among all, however, there are some that for the fantastic value for money do not really rivals, with often offers low-cost holiday packages, even in August. A single note to keep in mind: before you book, the less you spend! The crystalline and very clean water, the iridescent colored sand, which turn from dazzling white to bright pink, and its shallow and sandy bottoms make Policoro beach one of the hidden gems of Basilicata.
Access to the beach is controlled by WWF volunteers who protect and preserve these friendly animals, very often subject to high risk of extinction. Policoro is not only sun and sea, but also archeology and uncontaminated nature.
The history of the area tells of a glorious past linked to the glories of the Magna Graecia, of which you can admire evident traces in the National Archaeological Museum of Siritide, in the Sanctuary of Demeter and the Temple of Dionysus, even though in reality the city was founded in antecedent, around BC Another must-have stop is the baronial castle or Palazzo Berlingieri, built in the middle of the Middle Ages and rearranged on several occasions until the late 18th century.
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Because it is cheap: far from the usual circuits linked to mass tourism, the town of Policoro is still little known and is also for this reason that a holiday in this area offers very low costs.
Not very touristy and also far from the crowds that choose other locations, San Ferdinando is perfect for a beach holiday, relaxation, but also cultural visits. The strong point for sea lovers is its beautiful sandy beach that stretches for miles, kissed by a thick pine forest in which to find refreshment from the summer heat. But even at the historical-cultural level, do not mess around! It is in this area, in fact, that the Greek city of Medma stood, which left traces of its fertile presence with numerous finds of the era, and the entire area also tells of a prosperous Byzantine period.
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The IRB system is in trouble, and that means trouble for the safety and efficacy of research on human subjects. We should refocus our efforts on the core issues and stop expanding the mission into less productive territory. Gunsalus, Edward M. Bruner, Nicholas C. Goldberg, William T. Greenough, Gregory A. Miller, Michael G. Pratt Miller, and Michael G. Under harsh conditions, the researchers find that their models are consistent with a strong selection for increased birth weight among lambs, which is also associated with a low genetic variation.
Favorable conditions result in a reduced selection on birth weight. Thus, for this trait in Soay sheep, the environment acts as a constraint on the micro- evolutionary potential of the population. The rise of agriculture at the beginning of the Holocene era is thought to have contributed to large increases in ancient populations. One measure of population growth that can be evaluated with reasonable certainty based on archaeological evidence is the number of juve- niles in grave sites.
Growing popu- lations have proportionally more children, whereas the converse is true of populations in decline. Bocquet-Appel and Naji studied the skeleton records in 62 ancient North American cemeteries, and observed that local societal transi- tions from foraging to agriculture were followed by a significant increase in the juvenile aged 5 to 19 human remains. This trend par- allels a similar but earlier transition in Europe. Yet classical models of the genetics of populations often assume the simpli- fying condition of a constant environment, beg- ging the question of what happens to the heri- tability and selection of specific traits in times of change.
Details of the phenotype of Soay sheepfirst introduced to the Scottish archipel- ago of St. Kilda in the Bronze Age and to the main island of Hirta in have been col- lected since and provide a case study of microevolution through changeable times.
Wilson et al. It is transmitted by blood-sucking ticks, usually among deer and small mammals. But Ixodes ticks are not fussy and will feed on any vertebrate, including humans. As human activities encroach into wooded and heathland environments, we run the risk of tick infestation and possible Lyme disease transmission. For 13 years, Ostfeld et al. Classically, deer abundance and weather were thought to influence numbers of ticks and hence predict the risk of human infection, but it turns out that small mammal abundance over the previous year is a much better indicator.
Mice and chipmunks, whose numbers are determined by food supply in the prior year, are important hosts for the tiny juvenile stages of the ticks, which, because they are unnoticeable, tend not to be removed from the skin and can be extremely abundant in summer. Consequently, the acorn supply for mice and chipmunks 2 years previously makes an excellent measure of Lyme disease risk. Soay sheep. The global data hint that many foraging populations may have stagnated in the years approaching the various transitions, or even declined slightly on account of taxed resources or emerging diseases BH Curr.
Loss of algae from corals severely reduces nutrient flow through these ecosystems, with worrying impacts on the diversity and biomass of other reef-dwelling organisms, especially fish. Evidence is fast accu- mulating that warming events trigger these events. Less is known, however, about the ability of reef communities to recover from bleaching. Graham et al. A total of 50, m 2 were surveyed.
The structure of the reef habitats changed markedly after the death of branching and soft corals. By , the structural complexity of the reefs was reduced, and the habitats were dominated by rubble, encrusting corals, and algal fields. There were concomitant reductions in fish diversity, including some local extinctions. T cell anergy is associated with decreased interleukin 2 IL-2 production and decreased proliferation in response to antigen-specific stimulation.
Hundt et al. LAT serves as a scaffold recruiting various downstream effectors to the immunological synapse. There was no decrease in LAT abundance in the anergic cells, but LAT was selectively excluded from the immunological synapse because of reduced palmitoy- lation of LAT, which may explain the altered signaling properties in anergic T cells. NG Immunity 24, If bleaching events are regular, the prospects for recovery are not good. AMS Proc Natl. Local indentation probing is useful for hard metals or ceramics, but less so for soft materials.
The elastic modulus is a stiffness indicator but also reflects such properties as adhesion and swelling. Researchers are seeking alternative methods to measure complex samples such as a contact lens, which is small and soft and may need to be studied under hydrated conditions. Wilder et al. They measure the modulus of a compressed polymer by coating the surface with a stiffer material of known modulus.
Cannot ship outside U. Order Form Order online: www. Date Signature Unconditionally Guaranteed Custom-made library file cases! Each slipcase includes an attractive label with the Science logo. TNC Enterprises Dept. Box Warminster, PA One Modulus values from meas- urements of a model poly dimethylsiloxane system coated with a polystyrene film agreed well with those obtained from compression tests.
The technique can also quantify spatial variations in modulus through a single experi- ment, as demonstrated on a hydrogel sample that was prepared with a spatial concentration gradient of cross-linking agent. MSL Macromolecules 39, C HE MI S T RY Anion Induction In traditional asymmetric catalysis, a chiral cata- lyst binds directly to the reagent and thereby facilitates the reaction path to one product iso- mer while hindering the path to its enantiomer, or mirror image. Mayer and List show that asymmetric induction can also arise from pairing of an achiral cationic catalyst with a chi- ral counterion.
Chiral amine derivatives can promote transfer hydrogenation of ,-unsaturated aldehydes. The authors have now probed the same reaction class using protonated mor- pholine, an achiral amine, in combi- nation with binaphthol-based chiral phosphate anions. This catalyst sys- tem is particularly effective for aro- matic substrates, yielding product distributions that favor one enantiomer by or higher ratios. Sterically unhindered aliphatic sub- strates, such as citral and farnesal, are also reduced in high enantiomeric excess.
Because the reaction proceeds in aprotic solvent and requires a secondary, rather than tertiary, amine salt catalyst, the authors propose that induction occurs via an ion pair between the phosphate and an iminium intermediate, formed by amine displacement of the aldehyde oxygen.
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The effort to craft new biological components and systems or refine existing ones intrigues scientists, but it also raises questions about whether artificial bugs could harm human health or the environment. Tended by researchers at the Massachusetts Institute of Technology MIT and other universities, this meeting place for synthetic biol- ogists features a news roundup and listing of recent research and policy papers, including ones that led up to a meeting last month that pondered self-regulation of the field Science, 26 May, p.
By contrast, deep pits and gouges below reveal a tufted capuchin monkeys penchant for crunching nuts and seeds. Dental Microwear from paleoanthropologist Peter Ungar of the University of Arkansas, Fayetteville, offers an introduction to such microscopic clues to primate diets, including the dining habits of our ancient ancestors.
The site features background pages on studying tooth wear and a brief tutorial on one method called texture analysis. A database houses tooth-wear images for two monkey species and two types of early humans. Ungar hopes researchers will contribute results for many more vertebrates, from dinosaurs to humans. This unexpected side effect of a conservation measure caught the eye of geoscientist and environmental engineer Daniel Collins of the Massachusetts Institute of Technology.
His new blog Down to Earth brings a pragmatic attitude to discussions of ecosystem engineering, land use, natural hazards, and related subjects. Other topics that Collins has considered include safety concerns about a new dump for Hurricane Katrina refuse. It will also herald the reappearance of the Antarctic ozone hole, a thinning of Earths shield against ultraviolet radiation caused by humanmade chemicals.
The site also offers statistical summaries and maps of ozone readings dating back to Despite the phase-out of ozone- destroying chlorofluorocarbons, the hole remains large. In , for example, its average size during the peak period of September through October was 24 million square kilometersbelow s record of 26 million square kilometers but still the third largest on record left, September Visitors can also watch animations that follow the chemical reactions that gnaw at the ozone layer.
Relatives of DNA chips, the microarrays can help researchers identify proteins lurking in a drop of blood or a particular cell type and measure their concentrations. The software, which works for ELISA microarrays, can also help users gauge the reliability of their data.
To download it, visitors need to register by e-mail with the programs creators at the Pacific Northwest National Laboratory in Richland, Washington.
The awards are an interna- tionally recognized measure of excellence in science reporting for a general audience. They go to individuals rather than institutions, publishers or employers for coverage of the sciences, engineering and mathematics. Childrens Science News Deadline: August 1, www. The award is open to all regardless of nationality or citizenship.
Nominees must be living at the time of their nomination. All materials must be received by 1 August Below is Koreas latest entry, developed by the Korean Institute for Industrial Technology and unveiled last month. Unlike Japans Actroid, introduced in , EveR-1, as she is known, can look you in the eye because a camera that recognizes movement is located in the head. She can hold short conversations in Korean and English with her word vocabulary, moving her lips correspondingly.
She has 15 facial expressions and will show displeasure if you poke her. Her lower half has yet to be worked out, but scientists say EveR-1 can serve educational functions such as museum guide and reading to children. The first two Grand Challenges were desert runs.
This time, the autonomous machines will negotiate an urban environment. Their assignment: to safely complete a kilometer simulated military supply mission in under 6 hours, merging with traffic, avoid- ing obstacles, negotiating busy intersections, obeying traffic signals, executing U-turns, and finding alternate routes when necessary.
Only four vehicles completed last years Grand Challenge, which was won by Stanley, a souped-up Volkswagen Touareg above designed by a team at Stanford University. Final deadline for entry is 5 October Without the agricultural surpluses made possible by the shift some 10, years ago from hunting and gathering to farming, the rise of towns and cities would not have been possible.
But a survey of skeletal data from farming sites around the world shows that civilization took a toll on healthespecially dental health. Anthropologist Clark Larsen of Ohio State University in Columbus reviewed several dozen studies covering hundreds of skeletons from both hunter-gatherer and ancient farming societies. In the June issue of Quaternary International, he reports that farmers teeth show dramatically increased incidences of cavities compared to hunter-gatherers, probably as a result of eating more carbohydrate-loaded plants and less meat.
Whats more, a reduction in the size of the face and jaw, from eating softer foods such as cooked porridge, led to crowding of the teeth in the farmers. The shift away from meat eating also led to iron-deficiency anemia, as shown by a pathological increase in bone porosity in the skulls.
Higher population densities also took their toll, Clark reports, allowing infectious diseases such as syphilis, tuberculosis, and leprosyall of which leave telltale marks on the skeletonto spread much more readily.
Brian Hayden, an archaeologist at Simon Fraser University in Burnaby, Canada, speculates that the shift to farming also led to psychological stresses from increased population density: Health took a back seat right from the beginning.
Brain injuries can destroy the ability to recognize faces, and some people are born without the skill. Cognitive neuroscientist Bradley Duchaine of University College London and colleagues used the Internet to recruit participants and conduct a facial recognition survey. The subjects first viewed a face for 3 seconds. They were then presented with three face photos the original one and two othersand asked to indicate the one they recognized.
More difficult tests followed, in which participants were shown larger numbers of faces and asked whether they recognized people in different poses in altered lighting. The team, whose research is as yet unpublished, found that dozens of the subjects had serious enough problems with facial recognition that their daily lives would likely be affected. Its a neglected condition, says Duchaine.
Cognitive neuroscientist Martha Farah of the University of Pennsylvania calls prosopagnosics the ivory-billed woodpecker of neurological patients: They were rare, and some researchers even doubted that they existed. Duchaines team has found some cases in which prosopagnosia seems to run in the family, but the neurological and genetic bases for the condition remain to be unraveled.
Although the United States allows such interactions, the state has banned faculty members at Floridas public universities from having any contact with the island nation under a law enacted last week.
Cuba is one of six countries that the U. State Department has designated as a sponsor of t er rori sm, al t hough U.